Nonsteroidal Anti-Inflammatory Drugs (NSAIDs)
NSAIDs such as ibuprofen and naproxen are commonly prescribed for psoriatic arthritis to reduce pain and inflammation. They can help alleviate joint pain and stiffness, but they do not slow down disease progression. Long-term use of NSAIDs may increase the risk of gastrointestinal problems. NSAIDs are usually taken orally or applied topically in the form of creams or gels.
Disease-Modifying Antirheumatic Drugs (DMARDs)
DMARDs such as methotrexate, sulfasalazine, and leflunomide are commonly used for treating psoriatic arthritis. They work by suppressing the immune system to reduce inflammation and slow down joint damage. DMARDs may take several weeks to months to show their full effects. Regular monitoring is necessary when taking DMARDs to check for potential side effects.
Biologic Response Modifiers
Biologics such as adalimumab, etanercept, and ustekinumab are a newer class of medications for psoriatic arthritis. They target specific components of the immune system to reduce inflammation and control the disease. Biologics are usually prescribed for patients who do not respond to traditional DMARDs. These medications are usually administered through injections or intravenous infusions.
Corticosteroids
Corticosteroids such as prednisone and methylprednisolone are sometimes prescribed for psoriatic arthritis during flare-ups. They are potent anti-inflammatory medications that can provide rapid relief of symptoms. Long-term use of corticosteroids is generally avoided due to the risk of serious side effects. Corticosteroids may be taken orally, injected into joints, or applied topically.