Aminosalicylates
Aminosalicylates are anti-inflammatory drugs that can be effective in reducing the inflammation associated with Crohn's Disease. These medications work by targeting the lining of the gastrointestinal tract. They are often used to induce and maintain remission in mild to moderate cases of Crohn's Disease. Commonly prescribed examples include sulfasalazine, mesalamine, and olsalazine.
Corticosteroids
Corticosteroids are powerful anti-inflammatory drugs that can provide rapid relief from the symptoms of Crohn's Disease. They work by suppressing the immune system and reducing inflammation. Corticosteroids are typically used for short-term treatment to control flare-ups or induce remission. However, due to their potential side effects, long-term use is generally avoided. Commonly prescribed corticosteroids include prednisone and budesonide.
Immunomodulators
Immunomodulators are medications that work by suppressing the activity of the immune system. They help reduce inflammation and prevent the immune system from attacking the digestive tract. Immunomodulators are often used for long-term maintenance therapy in Crohn's Disease. Examples of immunomodulators used in Crohn's Disease treatment include azathioprine, mercaptopurine, and methotrexate.
Biologics
Biologic medications are a newer class of drugs that target specific components of the immune system involved in the inflammation of Crohn's Disease. They are usually prescribed for moderate to severe cases that have not responded well to other treatments. Biologics are administered via injection or infusion and can help induce and maintain remission. Examples of biologics commonly used for Crohn's Disease treatment include infliximab, adalimumab, and vedolizumab.