What causes tardive dyskinesia?

Tardive dyskinesia is a neurological disorder that causes involuntary and repetitive movements of the body. This article explores the possible causes of tardive dyskinesia and the factors that contribute to its development.

Medication-induced tardive dyskinesia

One of the primary causes of tardive dyskinesia is the use of certain medications, particularly antipsychotic drugs. Antipsychotic medications are commonly prescribed for the treatment of psychiatric disorders such as schizophrenia and bipolar disorder. Long-term use of these medications can lead to the development of tardive dyskinesia in some individuals. The exact mechanism by which these medications cause tardive dyskinesia is not fully understood, but it is believed to involve alterations in the dopamine system in the brain.

Other potential causes

In addition to medication-induced tardive dyskinesia, there are several other potential causes and risk factors that may contribute to its development. These include: 1. Duration of medication use: The risk of developing tardive dyskinesia increases with longer durations of medication use. 2. Age and gender: Older individuals and females may have a higher risk of developing tardive dyskinesia. 3. Genetic factors: Some studies suggest that certain genetic factors may predispose individuals to develop tardive dyskinesia. 4. Mental health conditions: People with certain mental health conditions, such as mood disorders and developmental disabilities, may be at a higher risk. 5. Substance abuse: Substance abuse and alcoholism have been associated with a higher risk of developing tardive dyskinesia. 6. Other medical conditions: Certain medical conditions, such as Parkinson's disease and Huntington's disease, may increase the risk. It is important to note that tardive dyskinesia can occur even in individuals who have not been exposed to any known risk factors, suggesting that there may be other contributing factors yet to be identified.